Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CASP2 | P42575 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329178 | 0.98 | HTT (0.35) | HTTCA1CA2MEN1KMT2A | |
| Water SCHEMBL15571107 | 0.96 | HTT (0.34) | HTTCA1CA2MEN1KMT2A | |
| Bromide SCHEMBL204549 | 0.96 | CA1 (0.36) | HTTCA1CA2MEN1KMT2A | |
| Iodide SCHEMBL1226177 | 0.96 | HTT (0.35) | HTTCA1CA2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4377339 | 0.94 | HTT (0.41) | HTTCA1CA2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4227151 | 0.92 | HTT (0.44) | HTTCA1CA2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5172897 | 0.92 | HTT (0.44) | HTTCA1CA2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5175241 | 0.92 | HTT (0.44) | HTTCA1CA2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5173929 | 0.92 | HTT (0.44) | HTTCA1CA2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2935144 | 0.92 | HTT (0.44) | HTTCA1CA2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112044406-A | Method for preparing microcrystalline cellulose/graphene oxide aerogel fibers from cotton barks | 大连工业大学 | 2020-12-08 | — | — | CN | claimed |
| EP-2601140-B1 | PROCESS FOR SEPARATING ZIRCONIUM AND HAFNIUM TETRACHLORIDES FROM MIXTURES THEREOF | CENTRE NAT RECH SCIENT (FR) | 2020-03-04 | — | — | EP | claimed |
| US-9005556-B2 | Process for separating zirconium and hafnium tetrachlorides from mixtures | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-04-14 | — | — | US | claimed |
| US-20130177488-A1 | PROCESS FOR SEPARATING ZIRCONIUM AND HAFNIUM TETRACHLORIDES FROM MIXTURES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUE (FR) | 2013-07-11 | — | — | US | claimed |
| WO-2013098052-A2 | METATHESIS OF NITRILE RUBBERS IN THE PRESENCE OF TRANSITION METAL COMPLEX CATALYSTS | LANXESS DEUTSCHLAND GMBH (DE) | 2013-07-04 | — | — | WO | claimed |
| WO-2013098056-A1 | PURIFICATION OF OPTIONALLY HYDROGENATED NITRILE RUBBER | LANXESS DEUTSCHLAND GMBH (DE) | 2013-07-04 | — | — | WO | claimed |
| US-20120328895-A1 | PRE-TREATMENT FOR PRESERVATION OF WOOD | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2012-12-27 | — | — | US | claimed |
| WO-2012170026-A1 | PRE-TREATMENT FOR PRESERVATION OF WOOD | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2012-12-13 | — | — | WO | claimed |
| US-8304563-B2 | Batch, semi-continuous or continuous hydrochlorination of glycerin with reduced volatile chlorinated hydrocarbon by-products and chloroacetone levels | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-11-06 | — | — | US | claimed |
| US-20110124890-A1 | BATCH, SEMI-CONTINUOUS OR CONTINUOUS HYDROCHLORINATIONOF GLYCERIN WITH REDUCED VOLATILE CHLORINATED HYDROCARBON BY-PRODUCTS AND CHLOROACETONE LEVELS | BLUE CUBE IP LLC | 2011-05-26 | — | — | US | claimed |
| US-7906690-B2 | Batch, semi-continuous or continuous hydrochlorination of glycerin with reduced volatile chlorinated hydrocarbon by-products and chloracetone levels | DOW GLOBAL TECHNOLOGIES INC. | 2011-03-15 | — | — | US | claimed |
| WO-2009102419-A2 | ALUMINUM RECOVERY PROCESS | THE UNIVERSITY OF ALABAMA (US) | 2009-08-20 | — | — | WO | claimed |
| WO-2008099203-A2 | REACTIONS OF ISOTOPICALLY ENRICHED ELEMENTS OF PHOSPHORUS, SULFUR, SELENIUM AND TELLURIUM | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2008-08-21 | — | — | WO | claimed |
| EP-1924589-A1 | REACTIONS OF GROUP 16 ELEMENTS | The Queen's Uni.Ionic Liquid Lab. Research Centre (GB) | 2008-05-28 | — | — | EP | claimed |
| US-20080015369-A1 | Batch, semi-continuous or continuous hydrochlorination of glycerin with reduced volatile chlorinated hydrocarbon by-products and chloracetone levels | BLUE CUBE IP LLC | 2008-01-17 | — | — | US | claimed |
| WO-2007020473-A1 | REACTIONS OF GROUP 16 ELEMENTS | THE QUEEN'S UNI.IONIC LIQUID LAB. RESEARCH CENTRE (GB) | 2007-02-22 | — | — | WO | claimed |
| EP-1432512-A1 | CATALYST COMPRISING INDIUM SALT AND ORGANIC IONIC LIQUID AND PROCESS FOR FRIEDEL-CRAFTS REACTIONS | The Queen's University of Belfast (GB) | 2004-06-30 | — | — | EP | claimed |
| WO-2003028883-A1 | CATALYST COMPRISING INDIUM SALT AND ORGANIC IONIC LIQUID AND PROCESS FOR FRIEDEL-CRAFTS REACTIONS | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2003-04-10 | — | — | WO | claimed |
| CN-112044406-A | Method for preparing microcrystalline cellulose/graphene oxide aerogel fibers from cotton barks | 大连工业大学 | 2020-12-08 | — | — | CN | disclosed |
| EP-0398358-A2 | Aluminum electroplating method | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124890-A1 | BATCH, SEMI-CONTINUOUS OR CONTINUOUS HYDROCHLORINATIONOF GLYCERIN WITH REDUCED VOLATILE CHLORINATED HYDROCARBON BY-PRODUCTS AND CHLOROACETONE LEVELS | GK, CHLSN, GLI2 | HTT 405/4885CA1 841/4885CA2 556/4885 |
| US-20080015369-A1 | Batch, semi-continuous or continuous hydrochlorination of glycerin with reduced volatile chlorinated hydrocarbon by-products and chloracetone levels | GK, GLI2, CHLSN | HTT 367/4885CA1 756/4885CA2 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.