Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 17/20 | 0.73 |
| ▸ | CDK4 | P11802 | 13/20 | 0.73 |
| ▸ | PLK1 | P53350 | 3/20 | 0.73 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.70 |
| ▸ | AURKA | O14965 | 6/20 | 0.62 |
| ▸ | CDK9 | P50750 | 6/20 | 0.62 |
| ▸ | CDK1 | P06493 | 5/20 | 0.62 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.62 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.62 |
| ▸ | ABL1 | P00519 | 2/20 | 0.62 |
| ▸ | GSK3B | P49841 | 2/20 | 0.62 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.62 |
| ▸ | CDC7 | O00311 | 1/20 | 0.62 |
| ▸ | PLK4 | O00444 | 1/20 | 0.62 |
| ▸ | CIT | O14578 | 1/20 | 0.62 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.62 |
| ▸ | GAK | O14976 | 1/20 | 0.62 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.62 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.62 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2281563 | 0.88 | CDK2 (0.76) | CDK2CDK4PLK1CCNE1AURKA | |
| SCHEMBL2283592 | 0.85 | CDK2 (0.73) | CDK2CDK4PLK1CCNE1AURKA | |
| SCHEMBL4797791 | 0.84 | CDK2 (0.78) | CDK2CDK4PLK1CCNE1AURKA | |
| SCHEMBL5052445 | 0.84 | CDK2 (1.00) | CDK2CDK4PLK1CCNE1AURKA | |
| SCHEMBL2073680 | 0.84 | CDK2 (0.78) | CDK2CDK4PLK1CCNE1AURKA | |
| SCHEMBL4799684 | 0.84 | CDK2 (0.78) | CDK2CDK4PLK1CCNE1AURKA | |
| SCHEMBL2076190 | 0.84 | CDK2 (0.78) | CDK2CDK4PLK1CCNE1AURKA | |
| SCHEMBL2287386 | 0.84 | CDK2 (0.58) | CDK2CDK4PLK1CCNE1AURKA | |
| SCHEMBL2289774 | 0.84 | CDK2 (0.58) | CDK2CDK4PLK1CCNE1AURKA | |
| SCHEMBL2283342 | 0.84 | CDK2 (0.77) | CDK2CDK4PLK1CCNE1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, RDX | CDK2 2065/4885CDK4 776/4885PLK1 4801/4885 |
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, CYP3A4 | CDK2 2144/4885CDK4 818/4885PLK1 4819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.