Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 17/20 | 0.58 |
| ▸ | CDK4 | P11802 | 11/20 | 0.58 |
| ▸ | AURKA | O14965 | 6/20 | 0.55 |
| ▸ | CDK9 | P50750 | 5/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.55 |
| ▸ | CDK7 | P50613 | 4/20 | 0.55 |
| ▸ | CDK1 | P06493 | 4/20 | 0.55 |
| ▸ | PLK1 | P53350 | 3/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | IKBKB | O14920 | 2/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.46 |
| ▸ | PAK4 | O96013 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | FYN | P06241 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2281563 | 0.86 | CDK2 (0.76) | CDK2CDK4AURKACDK9AURKB | |
| SCHEMBL14562209 | 0.85 | CDK2 (0.74) | CDK2CDK4AURKACDK9AURKB | |
| SCHEMBL2283552 | 0.84 | CDK2 (0.73) | CDK2CDK4AURKACDK9AURKB | |
| SCHEMBL2283592 | 0.83 | CDK2 (0.73) | CDK2CDK4AURKACDK9AURKB | |
| SCHEMBL2287386 | 0.82 | CDK2 (0.58) | CDK2CDK4AURKACDK9AURKB | |
| SCHEMBL2289719 | 0.82 | CDK2 (0.76) | CDK2CDK4AURKACDK9AURKB | |
| SCHEMBL2278842 | 0.79 | CDK2 (0.56) | CDK2CDK4AURKACDK9AURKB | |
| SCHEMBL2287240 | 0.78 | CDK2 (0.58) | CDK2CDK4AURKACDK9AURKB | |
| SCHEMBL2285515 | 0.76 | CDK2 (0.55) | CDK2CDK4AURKACDK9AURKB | |
| SCHEMBL14378915 | 0.74 | CDK2 (0.66) | CDK2CDK4AURKACDK9AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, RDX | CDK2 2065/4885CDK4 776/4885AURKA 2085/4885 |
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, CYP3A4 | CDK2 2144/4885CDK4 818/4885AURKA 2015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.