Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24427125 | 0.94 | HSP90AA1 (0.55) | ALDH1A1TSHRFAAHMEN1MAPK1 | |
| SCHEMBL24065982 | 0.90 | PAOX (0.52) | FAAHMEN1MAPK1KMT2AHSP90AA1 | |
| SCHEMBL24240988 | 0.89 | HDAC1 (0.44) | ALDH1A1TSHRFAAHMEN1MAPK1 | |
| SCHEMBL1842409 | 0.85 | CYP2C19 (0.48) | TSHRFAAHMEN1KMT2AHSP90AA1 | |
| SCHEMBL103082 | 0.84 | — | — | |
| SCHEMBL103896 | 0.82 | HSP90AA1 (0.67) | ALDH1A1TSHRFAAHMEN1MAPK1 | |
| SCHEMBL2248552 | 0.82 | HSP90AA1 (0.67) | ALDH1A1TSHRFAAHMEN1MAPK1 | |
| SCHEMBL734547 | 0.82 | HSP90AA1 (0.67) | ALDH1A1TSHRFAAHMEN1MAPK1 | |
| SCHEMBL18591622 | 0.82 | HSP90AA1 (0.67) | ALDH1A1TSHRFAAHMEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL6394231 | 0.82 | HSP90AA1 (0.60) | ALDH1A1TSHRFAAHMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10875888-B2 | Steroid derivative FXR agonist | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2020-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10875888-B2 | Steroid derivative FXR agonist | NR1H4, SLC10A1, FXR1 | ALDH1A1 1991/4885TSHR 492/4885FAAH 2930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.