Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2281296 | 0.89 | TSHR (0.39) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL2278328 | 0.85 | TSHR (0.39) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL4374381 | 0.82 | TSHR (0.44) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL7146706 | 0.82 | APEX1 (0.35) | TSHR | |
| SCHEMBL8523123 | 0.80 | CA2 (0.45) | TSHRCYP3A4ATMTDP1CA2 | |
| Acrylic Acid SCHEMBL5062877 | 0.79 | TSHR (0.45) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL11856397 | 0.79 | TSHR (0.42) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL2277103 | 0.77 | TSHR (0.35) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL2275748 | 0.77 | TSHR (0.40) | TSHRCYP3A4ATMTDP1CA2 | |
| SCHEMBL9408897 | 0.77 | CA2 (0.44) | TSHRCYP3A4ATMTDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989654-B2 | High purity bases of 3,3-diphenylpropylamino monoesters | UCB PHARMA GMBH (DE) | 2011-08-02 | — | — | US | disclosed |
| US-20090012159-A1 | HIGH PURITY BASES OF 3,3-DIPHENYLPROPYLAMINO MONOESTERS | UCB PHARMA GMBH (DE) | 2009-01-08 | — | — | US | disclosed |
| US-20060014832-A1 | Highly pure bases of 3,3-dipheyl propylamine monoesters | SCHWARZ PHARMA AG (DE) | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014832-A1 | Highly pure bases of 3,3-dipheyl propylamine monoesters | ADRB3, DRD3, CYP3A5 | TSHR 567/4885CYP3A4 76/4885ATM 2823/4885 |
| US-20090012159-A1 | HIGH PURITY BASES OF 3,3-DIPHENYLPROPYLAMINO MONOESTERS | CYP11B2, CYP11B1, CYP21A2 | TSHR 474/4885CYP3A4 59/4885ATM 4110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.