SCHEMBL22839714

SCHEMBL22839714

CO/C(C)=C(/C)c1cc(C)cc(C)c1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TPMT P51580 1/20 0.41
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
C1S P09871 1/20 0.39
PRSS3 P35030 1/20 0.39
CNR2 P34972 4/20 0.36
ALDH1A1 P00352 2/20 0.36
ATM Q13315 1/20 0.35
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
SLC7A5 Q01650 1/20 0.34
TDP1 Q9NUW8 1/20 0.32
TSHR P16473 1/20 0.32
HPGD P15428 1/20 0.31
HCAR1 Q9BXC0 1/20 0.31
ACHE P22303 1/20 0.31
CNR1 P21554 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21393194 0.74 TPMT (0.35) TPMTPRSS1PRSS2C1SPRSS3
SCHEMBL23847821 0.69 TAS1R3 (0.32) TPMTPRSS1PRSS2C1SPRSS3
Acetic Acid Methyl Ester SCHEMBL28118872 0.69 ALDH1A1 (0.59) TPMTCNR2ALDH1A1ATMTAS1R3
Methyl 3,5-Dimethylbenzoate SCHEMBL334346 0.68 CNR2 (0.66) TPMTCNR2ALDH1A1ATMSLC7A5
SCHEMBL5380375 0.68 TPMT (0.42) TPMTPRSS1PRSS2C1SPRSS3
SCHEMBL16953904 0.68 TPMT (0.52) TPMTPRSS1PRSS2C1SPRSS3
Methoxymethane SCHEMBL27501177 0.66 ALDH1A1 (0.53) TPMTPRSS1PRSS2C1SPRSS3
SCHEMBL11518139 0.66 ALDH1A1 (0.61) TPMTPRSS1PRSS2C1SPRSS3
SCHEMBL9482520 0.66 ALDH1A1 (0.61) TPMTPRSS1PRSS2C1SPRSS3
SCHEMBL25401798 0.66 ALDH1A1 (0.61) TPMTPRSS1PRSS2C1SPRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3541823-B1 CATALYSTS BOREALIS AG (AT) 2020-12-30 EP disclosed