Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19784609 | 0.89 | SIGMAR1 (0.43) | BCHEACHEMAOBTDP1DRD2 | |
| SCHEMBL22840000 | 0.87 | ACHE (0.43) | BCHEACHEMAOBDRD2DRD4 | |
| SCHEMBL22840007 | 0.79 | BCHE (0.51) | BCHEACHEMAOBDRD2DRD4 | |
| SCHEMBL22839814 | 0.78 | ACHE (0.46) | BCHEACHEMAOBDRD2DRD4 | |
| SCHEMBL19770210 | 0.74 | CHRM3 (0.62) | BCHEACHEMAOBDRD2DRD4 | |
| SCHEMBL19782549 | 0.74 | CHRM3 (0.55) | BCHEACHEMAOBTDP1CHRM3 | |
| SCHEMBL19784066 | 0.73 | CHRM3 (0.46) | BCHEACHEMAOBDRD2DRD4 | |
| SCHEMBL24404488 | 0.73 | BCHE (0.53) | BCHEACHEMAOBDRD2DRD4 | |
| SCHEMBL18557607 | 0.73 | ACHE (0.50) | BCHEACHEMAOBDRD2DRD4 | |
| SCHEMBL18557656 | 0.73 | POLB (0.51) | BCHEACHEMAOBDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484879-B1 | HYDROXYQUINOLINONE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2020-12-30 | — | — | EP | disclosed |