Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 10/20 | 0.34 |
| ▸ | MEP1A | Q16819 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22839942 | 0.88 | EPHX2 (0.33) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL22839818 | 0.87 | EPHX2 (0.34) | — | |
| SCHEMBL22839937 | 0.86 | NAMPT (0.33) | HDAC1HDAC3HDAC2NCOR2NAMPT | |
| SCHEMBL22839884 | 0.86 | HTT (0.35) | — | |
| SCHEMBL22839885 | 0.86 | P4HB (0.32) | — | |
| SCHEMBL22839829 | 0.85 | TSHR (0.32) | — | |
| SCHEMBL22839935 | 0.85 | PPARG (0.36) | HDAC1HDAC3HDAC2NCOR2NAMPT | |
| SCHEMBL22839961 | 0.83 | NAMPT (0.33) | HDAC1HDAC3HDAC2NCOR2NAMPT | |
| SCHEMBL22839962 | 0.83 | NAMPT (0.32) | NAMPT | |
| SCHEMBL22839877 | 0.81 | NAMPT (0.38) | HDAC1HDAC3HDAC2NCOR2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484879-B1 | HYDROXYQUINOLINONE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2020-12-30 | — | — | EP | disclosed |