Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22839818 | 0.91 | EPHX2 (0.34) | EPHX2 | |
| SCHEMBL22839884 | 0.90 | HTT (0.35) | EPHX2 | |
| SCHEMBL22839885 | 0.90 | P4HB (0.32) | — | |
| SCHEMBL22839829 | 0.89 | TSHR (0.32) | — | |
| SCHEMBL22839824 | 0.88 | HDAC1 (0.39) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL22839962 | 0.85 | NAMPT (0.32) | — | |
| SCHEMBL22839880 | 0.84 | — | — | |
| SCHEMBL22839893 | 0.84 | SSTR4 (0.32) | — | |
| SCHEMBL22839961 | 0.82 | NAMPT (0.33) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL22839951 | 0.82 | NAMPT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484879-B1 | HYDROXYQUINOLINONE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2020-12-30 | — | — | EP | disclosed |