SCHEMBL2283983

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2286801	0.89	KCNH2 (0.55)	DRD3KCNH2DRD2HRH1CHRM2
	SCHEMBL4877770	0.82	DRD3 (0.56)	DRD3KCNH2DRD2HRH1CHRM2
	SCHEMBL2283888	0.80	DRD3 (0.58)	DRD3KCNH2DRD2HRH1CHRM2
	SCHEMBL2283767	0.73	DRD3 (0.46)	DRD3KCNH2DRD2HRH1CHRM2
	Hydrochloric Acid SCHEMBL2283855	0.72	KCNH2 (0.98)	DRD3KCNH2DRD2HRH1CHRM2
	SCHEMBL17806216	0.67	NOTUM (0.42)	DRD3KCNH2DRD2HRH1CHRM2
	SCHEMBL17809621	0.65	ALDH1A1 (0.50)	DRD3KCNH2DRD2HRH1CHRM2
	SCHEMBL21254592	0.63	DRD3 (0.38)	DRD3KCNH2DRD2HRH1CHRM2
	SCHEMBL1639551	0.63	HRH3 (0.62)	HRH3
	SCHEMBL3491201	0.62	KDM4E (0.50)	KCNH2KDM4EALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.