Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22839907 | 0.78 | ADRB2 (0.45) | ADRB2DRD2 | |
| SCHEMBL22839832 | 0.77 | ADRB2 (0.40) | TDP1ADRB2 | |
| SCHEMBL22840003 | 0.76 | ADRB2 (0.50) | ADRB1ADRB2 | |
| SCHEMBL22839802 | 0.75 | KDM4E (0.40) | ADRB1ADRB2DRD2ADRA1DADRB3 | |
| SCHEMBL22839981 | 0.74 | ADRB2 (0.46) | ADRB2DRD2 | |
| SCHEMBL19784079 | 0.73 | ADRB2 (0.54) | ADRB1ADRB2DRD2ADRB3 | |
| SCHEMBL22829237 | 0.71 | ADRB2 (0.57) | ADRB1ADRB2ADRB3 | |
| SCHEMBL22829239 | 0.71 | ADRB2 (0.57) | ADRB1ADRB2ADRB3 | |
| SCHEMBL22839831 | 0.69 | TDP1 (0.49) | TDP1ADAM10MMP2MMP3MMP9 | |
| SCHEMBL22839848 | 0.68 | ADRB2 (0.36) | ADRB1ADRB2DRD2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484879-B1 | HYDROXYQUINOLINONE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2020-12-30 | — | — | EP | disclosed |