Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 15/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22839907 | 0.95 | ADRB2 (0.45) | ADRB2CHRM3DRD2DRD4 | |
| SCHEMBL19784370 | 0.83 | ADRB2 (0.50) | ADRB2CHRM3 | |
| SCHEMBL22839974 | 0.83 | ADRB2 (0.40) | ADRB2CHRM3DRD2DRD4 | |
| SCHEMBL19784600 | 0.82 | ADRB2 (0.40) | ADRB2CHRM3DRD2DRD4 | |
| SCHEMBL22839832 | 0.81 | ADRB2 (0.40) | ADRB2CHRM3 | |
| SCHEMBL22839873 | 0.79 | ADRB2 (0.56) | ADRB2CHRM3DRD2DRD4 | |
| SCHEMBL22839971 | 0.79 | ADRB2 (0.49) | ADRB2CHRM3 | |
| SCHEMBL22839991 | 0.79 | ADRB2 (0.52) | ADRB2CHRM3 | |
| SCHEMBL22839800 | 0.79 | ADRB2 (0.49) | ADRB2CHRM3 | |
| SCHEMBL22839902 | 0.79 | ADRB2 (0.37) | ADRB2CHRM3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484879-B1 | HYDROXYQUINOLINONE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2020-12-30 | — | — | EP | disclosed |