Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SELL | P14151 | 1/20 | 0.31 |
| ▸ | SELP | P16109 | 1/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22839802 | 0.74 | KDM4E (0.40) | ADRB2CHRM3ERN1SLC16A3MEN1 | |
| SCHEMBL22839991 | 0.74 | ADRB2 (0.52) | ADRB2CHRM3 | |
| SCHEMBL22839848 | 0.72 | ADRB2 (0.36) | ADRB2CHRM3 | |
| SCHEMBL22839918 | 0.71 | ADRB2 (0.47) | ADRB2CHRM3 | |
| SCHEMBL22839971 | 0.69 | ADRB2 (0.49) | ADRB2CHRM3MEN1KMT2A | |
| SCHEMBL22839800 | 0.69 | ADRB2 (0.49) | ADRB2CHRM3MEN1KMT2A | |
| SCHEMBL22829099 | 0.68 | ADRB2 (0.68) | ADRB2CHRM3 | |
| SCHEMBL22829100 | 0.68 | ADRB2 (0.68) | ADRB2CHRM3 | |
| SCHEMBL19903846 | 0.66 | ADRB2 (0.36) | ADRB2SLC16A3MEN1LMNAKMT2A | |
| SCHEMBL19784572 | 0.65 | ADRB2 (0.74) | ADRB2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484879-B1 | HYDROXYQUINOLINONE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2020-12-30 | — | — | EP | disclosed |