Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | XDH | P47989 | 2/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23223709 | 0.79 | ADRB2 (0.39) | ADRB2ADRB1ADRA2AADRA2BADRA2C | |
| SCHEMBL21573538 | 0.77 | ADRB2 (0.43) | ADRB2ADRB3RAB9AADRB1DRD2 | |
| SCHEMBL24404490 | 0.77 | ADRB2 (0.38) | ADRB2 | |
| SCHEMBL20373657 | 0.76 | ADRB2 (0.40) | ADRB2ADRB1DRD2DRD3 | |
| SCHEMBL24404566 | 0.75 | ADRB2 (0.40) | ADRB2 | |
| SCHEMBL21573495 | 0.74 | ADRB2 (0.42) | ADRB2ADRB1DRD2 | |
| SCHEMBL23223736 | 0.74 | ADRB2 (0.39) | ADRB2ADRB3RAB9AADRB1LMNA | |
| SCHEMBL23223711 | 0.67 | HTR2A (0.38) | ADRB2 | |
| SCHEMBL18602165 | 0.67 | ADRA2A (0.38) | ADRB2ADRB3CYP3A4NFKB1MAPK1 | |
| SCHEMBL22839900 | 0.67 | BACE1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928890-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2018-02-28 | — | — | EP | disclosed |