Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 16/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22840080 | 0.91 | FOLH1 (0.63) | FOLH1 | |
| SCHEMBL22840029 | 0.88 | FOLH1 (0.78) | FOLH1 | |
| SCHEMBL11977635 | 0.88 | FOLH1 (0.78) | FOLH1 | |
| SCHEMBL22840033 | 0.88 | FOLH1 (0.76) | FOLH1 | |
| SCHEMBL22839976 | 0.87 | FOLH1 (0.61) | FOLH1 | |
| SCHEMBL20312089 | 0.87 | FOLH1 (0.61) | FOLH1 | |
| SCHEMBL24585290 | 0.81 | FOLH1 (0.60) | FOLH1 | |
| SCHEMBL20312087 | 0.81 | FOLH1 (0.58) | FOLH1 | |
| SCHEMBL24585283 | 0.80 | FOLH1 (0.77) | FOLH1 | |
| SCHEMBL20312204 | 0.80 | FOLH1 (0.77) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3699162-B1 | HETERODIMERS OF GLUTAMIC ACID | MOLECULAR INSIGHT PHARM INC (US) | 2022-06-29 | — | — | EP | disclosed |