Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26711864 | 0.87 | NPSR1 (0.43) | LMNAHPGDGFERHSD17B10NPSR1 | |
| SCHEMBL24109490 | 0.80 | HSD17B10 (0.44) | LMNAHPGDGFERHSD17B10NR1H3 | |
| SCHEMBL10256676 | 0.75 | THRB (0.39) | LMNAHPGDHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL25023354 | 0.74 | NPSR1 (0.38) | LMNAHPGDGFERHSD17B10NPSR1 | |
| SCHEMBL21377208 | 0.72 | NPSR1 (0.41) | LMNAHPGDGFERHSD17B10NPSR1 | |
| SCHEMBL27308545 | 0.71 | KCNH2 (0.30) | — | |
| SCHEMBL13244532 | 0.70 | KCNH2 (0.44) | LMNAHPGDGFERHSD17B10NPSR1 | |
| SCHEMBL2741636 | 0.69 | HSP90AA1 (0.38) | LMNAHPGDGFERHSD17B10NPSR1 | |
| SCHEMBL19416297 | 0.68 | LMNA (0.44) | LMNAHPGDGFERHSD17B10NPSR1 | |
| SCHEMBL12545835 | 0.68 | HPGD (0.45) | LMNAHPGDGFERHSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484879-B1 | HYDROXYQUINOLINONE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2020-12-30 | — | — | EP | disclosed |