SCHEMBL2284196

SCHEMBL2284196

C=CC(=O)OCCC(O)OC(=O)C=C

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.52
ALDH1A1 P00352 4/20 0.52
TP53 P04637 3/20 0.52
HIF1A Q16665 3/20 0.52
CYP3A4 P08684 2/20 0.52
HSD17B10 Q99714 1/20 0.52
HPGD P15428 1/20 0.47
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
THRB P10828 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8965576 0.89 TSHR (0.59) TSHRALDH1A1TP53HIF1ACYP3A4
Methacrylic Acid SCHEMBL28331805 0.88 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL25309314 0.83 THRB (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL16243779 0.83 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28450987 0.82 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9669107 0.82 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9329300 0.81 TSHR (0.69) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL11233280 0.81 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL996461 0.81 TSHR (0.58) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL6368712 0.81 TSHR (0.58) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0620455-B1 Polymeric ophthalmic lens with crosslinker containing saccharide residue JOHNSON & JOHNSON VISION PROD (US) 2000-12-20 EP claimed
US-5690953-A SOFT HYDROGEL CONTACT LENSES JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) 1997-11-25 US claimed
EP-0620455-A2 Polymeric ophthalmic lens with crosslinker containing saccharide residue JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) 1994-10-19 EP claimed
EP-0182659-B1 SHAPED HYDROGEL ARTICLES JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) 1993-05-05 EP claimed
US-4680336-A SOFT CONTACT LENSES, DILUENTS VISTAKON, INC. (US) 1987-07-14 US claimed
EP-0182659-A2 Shaped hydrogel articles JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) 1986-05-28 EP claimed
CN-118389002-A Light scattering ink composition, color filter and image display device 东友精细化工有限公司 2024-07-26 CN disclosed
EP-1900503-B1 Method and mold for producing a contact lense COOPERVISION INT HOLDING CO LP (BB) 2019-09-04 EP disclosed
CN-109071258-A Inorganic oxide fine particles having amphiphilic organosilane compound bonded thereto, organic solvent dispersion liquid thereof, and composition for forming coating film 日产化学工业株式会社 2018-12-21 CN disclosed
CN-103391973-B Electrically conductive composition 纳美仕有限公司 2017-02-08 CN disclosed
CN-103304455-B Multifunctional sulfur generation (methyl) acrylate, resin combination and cured film, plastic foil, products formed, converted products 荒川化学工业株式会社 2016-12-28 CN disclosed
US-8003024-B2 Polyolefin contact lens molds and uses thereof COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2011-08-23 US disclosed
EP-1273430-B1 Consolidated contact lens molding JOHNSON & JOHNSON VISION PROD (US) 2008-11-12 EP disclosed
US-5064652-A WOUND DRESSING BAY MICHAEL (CH) 1991-11-12 US disclosed
EP-0355112-A1 CELL CULTURE PROCESSES, MATERIALS AND PRODUCTS Bay, Michael (CH) 1990-02-28 EP disclosed
WO-1988008448-A2 CELL CULTURE PROCESSES, MATERIALS AND PRODUCTS BAY MICHAEL (CH) 1988-11-03 WO disclosed
US-4680336-A SOFT CONTACT LENSES, DILUENTS VISTAKON, INC. (US) 1987-07-14 US disclosed
EP-0182659-A2 Shaped hydrogel articles JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) 1986-05-28 EP disclosed
US-4038264-A HYDROPHILIC POLYACRYLIC ESTERS, CONTACT LENSES NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1977-07-26 US disclosed
US-4009684-A Water soluble polymers useful in the preparation of novel animal litter NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1977-03-01 US disclosed