⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7673642 | 0.78 | — | — | |
| SCHEMBL7677863 | 0.73 | — | — | |
| SCHEMBL26972133 | 0.72 | — | — | |
| SCHEMBL1192072 | 0.71 | LMNA (0.32) | — | |
| SCHEMBL7671059 | 0.71 | — | — | |
| SCHEMBL24341909 | 0.67 | — | — | |
| SCHEMBL1192477 | 0.67 | — | — | |
| SCHEMBL19075386 | 0.67 | — | — | |
| SCHEMBL3382967 | 0.67 | — | — | |
| SCHEMBL1153637 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180494-B2 | Substituted amino acids as integrin inhibitors | PLIANT THERAPEUTICS, INC. (US) | 2021-11-23 | — | — | US | disclosed |
| WO-2020263967-A1 | 2H-INDAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | BIOGEN MA INC. (US) | 2020-12-30 | — | — | WO | disclosed |