Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | IARS1 | P41252 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391467 | 0.78 | MEN1 (0.50) | MEN1KMT2AALDH1A1IARS1 | |
| SCHEMBL2879514 | 0.78 | MCL1 (0.62) | MCL1HSD17B10LMNAMAPTHTT | |
| SCHEMBL6578464 | 0.77 | MCL1 (0.51) | MCL1HSD17B10LMNAMAPTHTT | |
| SCHEMBL22847851 | 0.76 | MCL1 (0.50) | MCL1HSD17B10LMNAMAPTHTT | |
| SCHEMBL12385783 | 0.75 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1NPC1GAA | |
| SCHEMBL6217575 | 0.74 | MCL1 (0.74) | MCL1HSD17B10LMNAMAPTHTT | |
| SCHEMBL6322096 | 0.74 | MCL1 (0.62) | MCL1LMNAHTTALDH1A1CYP2C19 | |
| SCHEMBL85848 | 0.74 | CYP2D6 (0.43) | MEN1KMT2ACYP2C19NPC1HPGD | |
| SCHEMBL14493157 | 0.74 | KMT2A (0.48) | HSD17B10HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL12523122 | 0.74 | MAPK1 (0.44) | HSD17B10MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200407324-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. | 2020-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200407324-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | ERCC4, ERCC1, F12 | MCL1 4732/4885HSD17B10 2732/4885LMNA 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.