Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16397384 | 0.90 | GAA (0.55) | KMT2APOLBKDM4ELMNAALDH1A1 | |
| SCHEMBL3090260 | 0.84 | POLB (0.67) | KMT2APOLBLMNAALDH1A1MEN1 | |
| SCHEMBL9494272 | 0.84 | CYP2C19 (0.58) | KMT2AKDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL22833103 | 0.84 | KDM4E (0.54) | KMT2AKDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL22833046 | 0.84 | KDM4E (0.54) | KMT2AKDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL22833186 | 0.84 | KDM4E (0.54) | KMT2AKDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL12270435 | 0.83 | KDM4E (0.62) | KMT2AKDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL9030520 | 0.83 | L3MBTL1 (0.68) | KMT2APOLBLMNAALDH1A1MEN1 | |
| SCHEMBL18172333 | 0.82 | KDM4E (0.50) | KMT2APOLBKDM4ELMNAALDH1A1 | |
| SCHEMBL1819402 | 0.82 | KDM4E (0.61) | KMT2AKDM4ELMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020260514-A1 | BIS(2-HALOACETAMIDO)-COMPOUNDS FOR USE AS LINKING AGENTS AND RESULTANT PRODUCTS WHICH COMPRISE ANTIBODIES, HALF-ANTIBODIES AND ANTIBODY FRAGMENTS | THE UNIVERSITY OF BATH (GB) | 2020-12-30 | — | — | WO | disclosed |