SCHEMBL22845406

SCHEMBL22845406

c1ccc(-c2nc(-c3ccc(-c4cccc(-c5ccc6c(c5)sc5c(-c7ccccc7)cccc56)c4)cc3)nc(-n3c4ccccc4c4ccccc43)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.39
LIMK1 P53667 12/20 0.37
PRKDC P78527 1/20 0.33
LIMK2 P53671 2/20 0.33
PIK3CA P42336 1/20 0.32
PI4KA P42356 1/20 0.32
PI4KB Q9UBF8 1/20 0.32
MAPK14 Q16539 1/20 0.31
MCL1 Q07820 1/20 0.31
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22845390 0.98 ALOX5 (0.42) ALOX5LIMK1PRKDCLIMK2PIK3CA
SCHEMBL22845440 0.93 ALOX5 (0.44) ALOX5LIMK1PRKDCPIK3CAMAPK14
SCHEMBL22329476 0.92 ALOX5 (0.38) ALOX5LIMK1PRKDCLIMK2PIK3CA
SCHEMBL22845242 0.92 ALOX5 (0.48) ALOX5LIMK1PRKDCPIK3CA
SCHEMBL22329968 0.92 LIMK1 (0.36) ALOX5LIMK1PRKDCLIMK2PIK3CA
SCHEMBL22845410 0.91 ALOX5 (0.39) ALOX5LIMK1PRKDCADORA2AADORA1
SCHEMBL22700435 0.91 ALOX5 (0.38) ALOX5LIMK1PRKDCLIMK2MAPK14
SCHEMBL22329970 0.91 ALOX5 (0.38) ALOX5LIMK1PRKDCLIMK2MAPK14
SCHEMBL22845247 0.91 LIMK1 (0.38) ALOX5LIMK1PRKDCMAPK14ADORA2A
SCHEMBL24303469 0.91 ALOX5 (0.45) ALOX5LIMK1PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200407348-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200407348-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD1, OXER1, OCIAD2 ALOX5 285/4885LIMK1 96/4885PRKDC 2766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.