SCHEMBL2284587

SCHEMBL2284587

Clc1cc2oc3ccccc3c2cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 9/20 1.00
MAPT P10636 4/20 0.53
KDM4E B2RXH2 3/20 0.53
ALDH1A1 P00352 3/20 0.53
HPGD P15428 3/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
MAOA P21397 3/20 0.47
LMNA P02545 1/20 0.47
PPARG P37231 1/20 0.47
NCOA2 Q15596 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
NCOR2 Q9Y618 1/20 0.47
GLA P06280 1/20 0.46
CYP3A4 P08684 1/20 0.46
PGAM1 P18669 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22136749 0.84 AHR (0.72) AHRMAPTKDM4EALDH1A1HPGD
SCHEMBL22136405 0.84 AHR (0.72) AHRMAPTKDM4EALDH1A1HPGD
SCHEMBL26027969 0.84 AHR (0.72) AHRMAPTKDM4EALDH1A1HPGD
SCHEMBL15840239 0.84 AHR (0.72) AHRMAPTKDM4EALDH1A1HPGD
SCHEMBL16919496 0.84 AHR (0.71) AHRMAPTKDM4EALDH1A1HPGD
SCHEMBL571563 0.84 AHR (0.71) AHRMAPTKDM4EALDH1A1HPGD
SCHEMBL29403123 0.83 AHR (1.00) AHRLMNAPPARGNCOA2NPSR1
SCHEMBL548471 0.83 AHR (1.00) AHRLMNAPPARGNCOA2NPSR1
SCHEMBL24156134 0.83 AHR (0.70) AHRMAPTKDM4EALDH1A1HPGD
SCHEMBL1635601 0.81 AHR (0.68) AHRMAPTKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020138726-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2020-07-02 WO disclosed
WO-2020138726-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2020-07-02 WO disclosed
US-7996156-B2 Methods for predicting properties of molecules THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2011-08-09 US disclosed