SCHEMBL15840239

SCHEMBL15840239

Nc1cc2oc3ccccc3c2cc1Cl

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.72
MAPT P10636 4/20 0.56
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
KDM4E B2RXH2 4/20 0.56
ALDH1A1 P00352 4/20 0.56
HPGD P15428 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
NQO1 P15559 1/20 0.47
TBK1 Q9UHD2 1/20 0.45
MAOA P21397 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
LMNA P02545 1/20 0.42
PPARG P37231 1/20 0.42
NCOA2 Q15596 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3886475 0.84 MAPT (0.64) AHRMAPTMEN1KMT2AKDM4E
SCHEMBL2284587 0.84 AHR (1.00) AHRMAPTMEN1KMT2AKDM4E
SCHEMBL22954455 0.80 AHR (0.54) AHRMAPTMEN1KMT2AKDM4E
SCHEMBL26027969 0.78 AHR (0.72) AHRMAPTMEN1KMT2AKDM4E
SCHEMBL22136405 0.78 AHR (0.72) AHRMAPTMEN1KMT2AKDM4E
SCHEMBL3705973 0.78 KDM4E (0.56) AHRMAPTMEN1KMT2AKDM4E
SCHEMBL25531245 0.78 HPGD (0.56) AHRMAPTMEN1KMT2AKDM4E
SCHEMBL26631793 0.78 KMT2A (0.56) AHRMAPTMEN1KMT2AKDM4E
SCHEMBL571563 0.77 AHR (0.71) AHRMAPTMEN1KMT2AKDM4E
SCHEMBL16919496 0.77 AHR (0.71) AHRMAPTMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230389423-A1 HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES UDC IRELAND LIMITED (IE) 2023-11-30 US disclosed
US-20230389423-A1 HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES UDC IRELAND LIMITED (IE) 2023-11-30 US disclosed
WO-2022079068-A1 HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-04-21 WO disclosed
WO-2021020799-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2021-02-04 WO disclosed
EP-3160954-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-09-23 EP disclosed
US-10644246-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2020-05-05 US disclosed
US-10227528-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2019-03-12 US disclosed
EP-2935276-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-11-01 EP disclosed
US-20170141327-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-05-18 US disclosed
US-20170141327-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-05-18 US disclosed
US-20150337197-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-20150337197-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
WO-2014094963-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2014-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10227528-B2 Materials for organic electroluminescent devices OR10J3, EPCAM, L1CAM AHR 3343/4885MAPT 874/4885MEN1 1650/4885
US-10644246-B2 Materials for organic electroluminescent devices OR10J3, EPCAM, L1CAM AHR 3310/4885MAPT 679/4885MEN1 1294/4885
US-20230389423-A1 HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES DDT, VDAC2, KCNC1 AHR 715/4885MAPT 2328/4885MEN1 1667/4885
US-20170141327-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES OR10J3, EPCAM, L1CAM AHR 3310/4885MAPT 679/4885MEN1 1294/4885
US-20150337197-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES OR10J3, EML4, L1CAM AHR 3164/4885MAPT 941/4885MEN1 1571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.