SCHEMBL548471

SCHEMBL548471

Clc1cc2oc3cc(Cl)c(Cl)cc3c2cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AHR P35869 17/20 1.00
DAO P14920 1/20 0.44
LMNA P02545 1/20 0.39
PPARG P37231 1/20 0.39
NCOA2 Q15596 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
NCOR2 Q9Y618 1/20 0.39
KMO O15229 1/20 0.39
FLT1 P17948 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29403123 1.00 AHR (1.00) AHRDAOLMNAPPARGNCOA2
SCHEMBL13672099 0.85 AHR (0.73) AHRDAO
SCHEMBL6466778 0.85 AHR (0.73) AHRDAONPSR1
SCHEMBL8952247 0.85 AHR (0.73) AHRNPSR1
SCHEMBL2278885 0.83 AHR (0.77) AHRDAOLMNA
SCHEMBL2280668 0.83 AHR (1.00) AHRLMNA
SCHEMBL2284587 0.83 AHR (1.00) AHRLMNAPPARGNCOA2NPSR1
SCHEMBL10648487 0.80 KDM4E (0.72) AHRLMNANPSR1RXFP1
SCHEMBL10356788 0.78 AHR (0.64) AHRLMNAPPARGNCOA2NPSR1
SCHEMBL29349569 0.78 AHR (1.00) AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4414356-A2 HIGHLY UNSATURATED FATTY ACID OR HIGHLY UNSATURATED FATTY ACID ETHYL ESTER WITH REDUCED ENVIRONMENTAL POLLUTANTS, AND METHOD FOR PRODUCING SAME Nissui Corporation (JP) 2024-08-14 EP claimed
EP-3971165-B1 HIGHLY UNSATURATED FATTY ACID OR HIGHLY UNSATURATED FATTY ACID ETHYL ESTER WITH REDUCED ENVIRONMENTAL POLLUTANTS, AND METHOD FOR PRODUCING SAME NISSUI CORP (JP) 2024-08-07 EP claimed
CN-114414719-A Method for rapidly extracting and purifying dioxin compounds in waste gas 光大理工环境技术研究院(青岛)有限公司 2022-04-29 CN claimed
CN-114397383-A Instrument analysis and detection method for dioxin substances in flue gas 光大理工环境技术研究院(青岛)有限公司 2022-04-26 CN claimed
EP-2851361-B1 HIGHLY UNSATURATED FATTY ACID OR HIGHLY UNSATURATED FATTY ACID ETHYL ESTER WITH REDUCED ENVIRONMENTAL POLLUTANTS, AND METHOD FOR PRODUCING SAME NIPPON SUISAN KAISHA LTD (JP) 2021-11-24 EP claimed
CN-110612119-A Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents 西雅图儿童医院(DBA西雅图儿童研究所) 2019-12-24 CN claimed
US-6720431-B2 SOLVENT EXTRACTION XENOBIOTIC DETECTION SYSTEMS INTERNATIONAL, INC. 2004-04-13 US claimed
JP-2004508539-A 2004-03-18 JP claimed
EP-1353741-A2 METHODS AND APPARATUS FOR SEPARATING AND DETECTING SPECIFIC POLYHALOGENATED DIAROMATIC HYDROCARBONS Xenobiotic Detection Systems International, Inc. (US) 2003-10-22 EP claimed
US-20020035303-A1 Methods and apparatus for separating and detecting specific polyhalogenated diaromatic hydrocarbons XENOBIOTIC DETECTION SYSTEMS INTERNATIONAL, INC. 2002-03-21 US claimed
US-5674697-A High sensitivity immunoassay for polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans ECOCHEM RESEARCH, INC. (US) 1997-10-07 US claimed
WO-1997017601-A1 PROCESS FOR EXTRACTING COMPOUNDS FROM SAMPLE MATRICES TRIANGLE LABORATORIES, INC. (US) 1997-05-15 WO claimed
EP-0480476-B1 Method for removing polychlorinated dibenzodioxins and polychlorinated dibenzofurans and stickies from secondary fibers KIMBERLY CLARK CO (US) 1996-05-22 EP claimed
EP-0480474-B1 Method for removing polyclorinated dibenzodioxins and polychlorinated dibenzofurans from paper mill sludge KIMBERLY CLARK CO (US) 1995-02-15 EP claimed
EP-0251635-B1 Monoclonal antibodies and method for detecting dioxins and dibenzofurans UNIV CALIFORNIA (US) 1994-08-10 EP claimed
EP-0480474-A1 Method for removing polyclorinated dibenzodioxins and polychlorinated dibenzofurans from paper mill sludge KIMBERLY-CLARK CORPORATION (US) 1992-04-15 EP claimed
EP-0480476-A1 Method for removing polychlorinated dibenzodioxins and polychlorinated dibenzofurans and stickies from secondary fibers KIMBERLY-CLARK CORPORATION (US) 1992-04-15 EP claimed
US-5075017-A Supercritical water oxidation under pressure yields ash, carbon dioxide KIMBERLY-CLARK CORPORATION (US) 1991-12-24 US claimed
US-5074958-A Pretreatment of waste paper for reuse KIMBERLY-CLARK CORPORATION (US) 1991-12-24 US claimed
US-5009745-A Treating cellulose-containing wastes KIMBERLY-CLARK CORPORATION (US) 1991-04-23 US claimed