Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC1 | P48995 | 3/20 | 0.51 |
| ▸ | TRPC3 | Q13507 | 3/20 | 0.51 |
| ▸ | STIM1 | Q13586 | 3/20 | 0.51 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.51 |
| ▸ | STIM2 | Q9P246 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | ESRRA | P11474 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 4/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29530969 | 1.00 | TRPC1 (0.51) | TRPC1TRPC3STIM1ORAI1STIM2 | |
| SCHEMBL22846560 | 0.93 | TRPC1 (0.46) | TRPC1TRPC3STIM1ORAI1STIM2 | |
| SCHEMBL22845780 | 0.87 | TRPC1 (0.45) | TRPC1TRPC3STIM1ORAI1STIM2 | |
| SCHEMBL29530958 | 0.87 | TRPC1 (0.45) | TRPC1TRPC3STIM1ORAI1STIM2 | |
| SCHEMBL29530726 | 0.86 | P2RY14 (0.49) | NOTUMP2RY14PRSS12OPRD1SIGMAR1 | |
| SCHEMBL22845777 | 0.86 | P2RY14 (0.49) | NOTUMP2RY14PRSS12OPRD1SIGMAR1 | |
| SCHEMBL22833942 | 0.85 | P2RY14 (0.41) | TRPC1TRPC3STIM1ORAI1STIM2 | |
| SCHEMBL29530717 | 0.85 | NME4 (0.51) | TRPC1TRPC3STIM1ORAI1STIM2 | |
| SCHEMBL22833966 | 0.85 | NME4 (0.51) | TRPC1TRPC3STIM1ORAI1STIM2 | |
| SCHEMBL21121983 | 0.84 | P2RY14 (0.47) | TRPC1TRPC3STIM1ORAI1STIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020263703-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | STRATOS GENOMICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |