Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 16/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29530726 | 1.00 | P2RY14 (0.49) | P2RY14OPRD1SIGMAR1KCNH2NOTUM | |
| SCHEMBL22833946 | 0.92 | P2RY14 (0.50) | P2RY14OPRD1SIGMAR1KCNH2NOTUM | |
| SCHEMBL22833936 | 0.89 | PRSS12 (0.46) | P2RY14OPRD1SIGMAR1NOTUMPRSS12 | |
| SCHEMBL22834185 | 0.89 | RXRA (0.48) | P2RY14OPRD1SIGMAR1NOTUMPRSS12 | |
| SCHEMBL22833959 | 0.88 | P2RY14 (0.61) | P2RY14OPRD1SIGMAR1KCNH2PRSS12 | |
| SCHEMBL22833942 | 0.87 | P2RY14 (0.41) | P2RY14OPRD1SIGMAR1KCNH2NOTUM | |
| SCHEMBL21121983 | 0.86 | P2RY14 (0.47) | P2RY14OPRD1SIGMAR1KCNH2NOTUM | |
| SCHEMBL22846402 | 0.86 | P2RY14 (0.50) | P2RY14OPRD1SIGMAR1NOTUMPRSS12 | |
| SCHEMBL22846017 | 0.86 | TRPC1 (0.51) | P2RY14OPRD1SIGMAR1NOTUMPRSS12 | |
| SCHEMBL29530851 | 0.86 | P2RY14 (0.50) | P2RY14OPRD1SIGMAR1NOTUMPRSS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020263703-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | STRATOS GENOMICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |