SCHEMBL22846019

SCHEMBL22846019

Cc1c(OC(F)(F)c2c(F)cc(-c3ccc(C4OCCCO4)cc3F)cc2F)cc(F)c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25574676 0.90
SCHEMBL29336401 0.88
SCHEMBL20869343 0.87 PRKAG1 (0.35)
SCHEMBL19680095 0.87
SCHEMBL24337148 0.85
SCHEMBL19680096 0.85
SCHEMBL17033199 0.85 CYP11B1 (0.33) CYP11B1CYP11B2
SCHEMBL19680100 0.84
SCHEMBL19680098 0.83
SCHEMBL19679586 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11739267-B2 LC medium MERCK PATENT GMBH (DE) 2023-08-29 US disclosed
US-20200407640-A1 LC MEDIUM MERCK PATENT GMBH (DE) 2020-12-31 US disclosed