SCHEMBL22848428

SCHEMBL22848428

O=C1C(=C/C=C2/N(Cc3ccncc3)c3ccc4ccccc4c3C23CCCCC3)C(=O)c2cc3ccccc3cc21

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
CASP3 P42574 1/20 0.32
MAPK8 P45983 1/20 0.32
MAPK9 P45984 1/20 0.32
MAPK10 P53779 1/20 0.32
PDE4A P27815 3/20 0.31
PDE4B Q07343 3/20 0.31
PDE4C Q08493 3/20 0.31
PDE4D Q08499 3/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22848246 0.78 HSP90AA1 (0.34) ALDH1A1
SCHEMBL22849183 0.77 PRMT1 (0.45) CASP3PDE4DALDH1A1
SCHEMBL22849283 0.77 ATM (0.31) ALDH1A1
SCHEMBL22848429 0.76 DRD2 (0.34) CA2
SCHEMBL22848447 0.76
SCHEMBL22848485 0.75 HTT (0.32) ALDH1A1
SCHEMBL22848219 0.75 KDM4E (0.31) ALDH1A1
SCHEMBL22848232 0.75 KDM4E (0.31) ALDH1A1
SCHEMBL22848201 0.72 POLB (0.31)
SCHEMBL22848433 0.70 PRMT1 (0.57) PDE4DALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11171165-B2 Photoelectric conversion element, imaging element, optical sensor comprising a photoelectric conversion film containing a predetermined compound, and compound FUJIFILM CORPORATION (JP) 2021-11-09 US disclosed
US-20200411569-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2020-12-31 US disclosed