Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 13/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22848185 | 0.86 | KRAS (0.34) | KRAS | |
| SCHEMBL24372814 | 0.71 | KRAS (0.35) | KRAS | |
| SCHEMBL26527390 | 0.71 | KRAS (0.42) | KRAS | |
| SCHEMBL26036624 | 0.69 | KRAS (0.32) | KRAS | |
| SCHEMBL29614930 | 0.69 | KRAS (0.54) | KRAS | |
| SCHEMBL24436419 | 0.69 | KRAS (0.54) | KRAS | |
| SCHEMBL20805455 | 0.68 | KRAS (0.45) | KRAS | |
| SCHEMBL26525295 | 0.68 | KRAS (0.51) | KRAS | |
| SCHEMBL22848330 | 0.68 | KRAS (0.41) | KRAS | |
| SCHEMBL20805634 | 0.68 | KRAS (0.49) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020259513-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF KRAS G12C | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2020-12-30 | — | — | WO | disclosed |