SCHEMBL22848376

SCHEMBL22848376

C=C1N(c2ccc3c(c2)C(C)(C)c2ccccc2-3)c2cc3c(cc2C12c1ccccc1-c1ccccc12)-c1ccccc1C3(C)C

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PGR P06401 10/20 0.34
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
PDK2 Q15119 2/20 0.30
PTH1R Q03431 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22848499 0.90 PGR (0.36) PGRMEN1KMT2APDK2
SCHEMBL22848378 0.80 LMNA (0.40) PGRMEN1KMT2APTH1R
SCHEMBL15030647 0.77 PGR (0.32) PGRMEN1KMT2APTH1R
SCHEMBL19368065 0.77 PGR (0.34) PGRMEN1KMT2APDK2
SCHEMBL21324526 0.76 PGR (0.36) PGRMEN1KMT2A
SCHEMBL16892755 0.76 PDK2 (0.38) PGRMEN1KMT2APDK2
SCHEMBL20915067 0.76 PGR (0.31) PGR
SCHEMBL20936077 0.76 PGR (0.31) PGR
SCHEMBL16900618 0.75 PGR (0.43) PGRMEN1KMT2A
SCHEMBL16900628 0.75 PGR (0.43) PGRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11171165-B2 Photoelectric conversion element, imaging element, optical sensor comprising a photoelectric conversion film containing a predetermined compound, and compound FUJIFILM CORPORATION (JP) 2021-11-09 US disclosed
US-20200411569-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2020-12-31 US disclosed