SCHEMBL22848464

SCHEMBL22848464

Cc1cc(C)c(N2/C(=C\C=C3C(=O)c4c(Cl)c(Cl)c(Cl)c(Cl)c4C3=O)C3(CCCCC3)c3c2ccc2c3C(C)(C)c3ccccc3-2)c(C)c1

nearest known ligand 0.30

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.30
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
USP2 O75604 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22848456 0.82 TP53 (0.31) MAPT
SCHEMBL22849340 0.81 PGR (0.30) PGR
SCHEMBL22848188 0.80 TP53 (0.31) MAPT
SCHEMBL22848477 0.79 KMT2A (0.31) KMT2A
SCHEMBL22848466 0.78 ALKBH5 (0.32) NPC1RAB9A
SCHEMBL22848494 0.78 NMT1 (0.30)
SCHEMBL22848473 0.78 KDM4E (0.30) MAPTSMN1; SMN2
SCHEMBL22848459 0.77 SMN1; SMN2 (0.30) SMN1; SMN2
SCHEMBL22848458 0.77
SCHEMBL22849284 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11171165-B2 Photoelectric conversion element, imaging element, optical sensor comprising a photoelectric conversion film containing a predetermined compound, and compound FUJIFILM CORPORATION (JP) 2021-11-09 US disclosed
US-20200411569-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2020-12-31 US disclosed