SCHEMBL22848484

SCHEMBL22848484

Cc1cc(C)c(N2/C(=C/C=C3C(=O)c4nccnc4C3=O)C(C)(C)c3c2ccc2ccccc32)c(C)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 7/20 0.35
LMNA P02545 6/20 0.33
MEN1 O00255 5/20 0.33
KMT2A Q03164 5/20 0.33
MAPT P10636 5/20 0.33
HTT P42858 4/20 0.33
TDP1 Q9NUW8 3/20 0.33
THRB P10828 2/20 0.33
RECQL P46063 2/20 0.33
KDM4E B2RXH2 2/20 0.33
APEX1 P27695 1/20 0.33
PRMT5 O14744 1/20 0.31
PRMT8 Q9NR22 1/20 0.31
BLM P54132 2/20 0.31
ALDH1A1 P00352 4/20 0.30
L3MBTL1 Q9Y468 3/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
NPC1 O15118 1/20 0.30
POLB P06746 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22848489 0.92 PRMT1 (0.33) PRMT1LMNAMEN1KMT2AMAPT
SCHEMBL22848254 0.88 PRMT1 (0.36) PRMT1LMNAMEN1KMT2AMAPT
SCHEMBL22848401 0.83 PRMT1 (0.37) PRMT1LMNAMEN1KMT2AMAPT
SCHEMBL22848221 0.82 CYP1A2 (0.33) PRMT1LMNAMEN1KMT2AMAPT
SCHEMBL25165432 0.80 PRMT1 (0.31) PRMT1MEN1KMT2AMAPTHTT
SCHEMBL22848191 0.80 PRMT1 (0.31) PRMT1MEN1KMT2AMAPTHTT
SCHEMBL22848196 0.79 PRMT1 (0.30) PRMT1
SCHEMBL22848465 0.79 MEN1 (0.31) MEN1KMT2AALDH1A1GAA
SCHEMBL25165339 0.79 MAPT (0.40) LMNAMEN1KMT2AMAPTHTT
SCHEMBL22848164 0.79 PRMT1 (0.37) PRMT1LMNAMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11171165-B2 Photoelectric conversion element, imaging element, optical sensor comprising a photoelectric conversion film containing a predetermined compound, and compound FUJIFILM CORPORATION (JP) 2021-11-09 US disclosed
US-20200411569-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2020-12-31 US disclosed