SCHEMBL22848489

SCHEMBL22848489

Cc1cc(C)c(N2/C(=C/C=C3\C(=O)c4cccnc4C3=O)C(C)(C)c3c2ccc2ccccc32)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 4/20 0.33
IDO1 P14902 2/20 0.32
MEN1 O00255 3/20 0.32
MAPT P10636 3/20 0.32
HTT P42858 3/20 0.32
KMT2A Q03164 3/20 0.32
RECQL P46063 2/20 0.32
USP2 O75604 2/20 0.32
RAB9A P51151 2/20 0.32
TOP2A P11388 1/20 0.32
PTPRC P08575 2/20 0.32
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
THRB P10828 1/20 0.31
APEX1 P27695 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CTSL P07711 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22848484 0.92 PRMT1 (0.35) PRMT1MEN1MAPTHTTKMT2A
SCHEMBL22848254 0.88 PRMT1 (0.36) PRMT1MEN1MAPTHTTKMT2A
SCHEMBL22848221 0.81 CYP1A2 (0.33) PRMT1MEN1MAPTHTTKMT2A
SCHEMBL25165432 0.81 PRMT1 (0.31) PRMT1MEN1MAPTHTTKMT2A
SCHEMBL22848191 0.81 PRMT1 (0.31) PRMT1MEN1MAPTHTTKMT2A
SCHEMBL22848401 0.80 PRMT1 (0.37) PRMT1MEN1MAPTHTTKMT2A
SCHEMBL22848196 0.79 PRMT1 (0.30) PRMT1
SCHEMBL22848164 0.79 PRMT1 (0.37) PRMT1MEN1MAPTHTTKMT2A
SCHEMBL25165423 0.79 PRMT1 (0.35) PRMT1MEN1MAPTHTTKMT2A
SCHEMBL22848465 0.78 MEN1 (0.31) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11171165-B2 Photoelectric conversion element, imaging element, optical sensor comprising a photoelectric conversion film containing a predetermined compound, and compound FUJIFILM CORPORATION (JP) 2021-11-09 US disclosed
US-20200411569-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2020-12-31 US disclosed