SCHEMBL22848191

SCHEMBL22848191

Cc1cc(C)c(N2/C(=C/C=C3\C(=O)c4ccccc4C3=C(C#N)C#N)C(C)(C)c3c2ccc2ccccc32)c(C)c1

nearest known ligand 0.31

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 3/20 0.31
KMT2A Q03164 2/20 0.31
MAPT P10636 2/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
USP2 O75604 1/20 0.31
POLB P06746 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25165432 1.00 PRMT1 (0.31) PRMT1KMT2AMAPTMEN1NPC1
SCHEMBL22848254 0.85 PRMT1 (0.36) PRMT1KMT2AMAPTMEN1NPC1
SCHEMBL25849800 0.84 KMT2A (0.42) PRMT1KMT2AMAPTMEN1NPC1
SCHEMBL25850882 0.83 PRMT1 (0.34) PRMT1KMT2AMAPTMEN1NPC1
SCHEMBL22848489 0.81 PRMT1 (0.33) PRMT1KMT2AMAPTMEN1NPC1
SCHEMBL22848436 0.80
SCHEMBL22848484 0.80 PRMT1 (0.35) PRMT1KMT2AMAPTMEN1NPC1
SCHEMBL22848221 0.79 CYP1A2 (0.33) PRMT1KMT2AMAPTMEN1NPC1
SCHEMBL22848401 0.77 PRMT1 (0.37) PRMT1KMT2AMAPTMEN1NPC1
SCHEMBL22848196 0.77 PRMT1 (0.30) PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11171165-B2 Photoelectric conversion element, imaging element, optical sensor comprising a photoelectric conversion film containing a predetermined compound, and compound FUJIFILM CORPORATION (JP) 2021-11-09 US disclosed
US-20200411569-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2020-12-31 US disclosed