Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL734566 | 1.00 | — | — | |
| SCHEMBL788 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL27385408 | 0.97 | MEN1 (0.46) | MEN1KMT2AHTTCA12CA1 | |
| Hydrochloric Acid SCHEMBL1500348 | 0.97 | MEN1 (0.46) | MEN1KMT2AHTTCA12CA1 | |
| SCHEMBL31411200 | 0.97 | MEN1 (0.46) | MEN1KMT2AHTTCA12CA1 | |
| Hydrochloric Acid SCHEMBL28013356 | 0.94 | MEN1 (0.44) | MEN1KMT2AHTTCA12CA1 | |
| Acetic Acid SCHEMBL28079072 | 0.87 | NPSR1 (0.46) | MEN1KMT2AHTTCA12CA1 | |
| Sulfuric Acid SCHEMBL8572112 | 0.85 | CA12 (0.52) | MEN1KMT2AHTTCA12CA1 | |
| Methanesulfonamide SCHEMBL9725954 | 0.85 | CA2 (0.57) | MEN1KMT2AHTTCA12CA1 | |
| Formic Acid SCHEMBL27578333 | 0.85 | KMT2A (0.43) | MEN1KMT2AHTTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020264499-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |