⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22849035 | 1.00 | MEN1 (0.48) | — | |
| SCHEMBL788 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL27385408 | 0.97 | MEN1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL1500348 | 0.97 | MEN1 (0.46) | — | |
| SCHEMBL31411200 | 0.97 | MEN1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL28013356 | 0.94 | MEN1 (0.44) | — | |
| Acetic Acid SCHEMBL28079072 | 0.87 | NPSR1 (0.46) | — | |
| Sulfuric Acid SCHEMBL8572112 | 0.85 | CA12 (0.52) | — | |
| Methanesulfonamide SCHEMBL9725954 | 0.85 | CA2 (0.57) | — | |
| Formic Acid SCHEMBL27578333 | 0.85 | KMT2A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170014468-A1 | METHODS OF USE FOR THERAPEUTICS TARGETING THE PATHOGEN PORPHYROMONAS GINGIVALIS | Cortexyme, Inc. | 2017-01-19 | — | — | US | claimed |
| EP-1333024-B1 | PEPTIDE DERIVATIVES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, PROCESSES FOR PREPARATION OF BOTH, AND USE THEREOF | UNIV KYUSHU NAT UNIV CORP (JP) | 2009-01-07 | — | — | EP | claimed |
| US-6951843-B2 | Peptide derivatives and their pharmaceutically acceptable salts, thereof, processes for preparation of both and use thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2005-10-04 | — | — | US | claimed |
| EP-1333024-A1 | PEPTIDE DERIVATIVES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, PROCESSES FOR PREPARATION OF BOTH, AND USE THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2003-08-06 | — | — | EP | claimed |
| US-20030087828-A1 | Peptide derivatives and pharmaceutically acceptable salts, thereof, processes for preparation of both, and use thereof | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2003-05-08 | — | — | US | claimed |
| US-20200060995-A1 | Substituted Phenethylamines With Serotoninergic And/Or Norepinephrinergic Activity | ACADIA PHARMACEUTICALS INC. | 2020-02-27 | — | — | US | disclosed |
| US-20180256517-A1 | Substituted Phenethylamines With Serotoninergic And/Or Norepinephrinergic Activity | ACADIA PHARMACEUTICALS INC. | 2018-09-13 | — | — | US | disclosed |
| US-20180085327-A1 | Substituted Phenethylamines With Serotoninergic And/Or Norepinephrinergic Activity | ACADIA PHARMACEUTICALS INC. | 2018-03-29 | — | — | US | disclosed |
| US-20170014468-A1 | METHODS OF USE FOR THERAPEUTICS TARGETING THE PATHOGEN PORPHYROMONAS GINGIVALIS | Cortexyme, Inc. | 2017-01-19 | — | — | US | disclosed |
| US-20160361275-A1 | SUBSTITUTED PHENETHYLAMINES WITH SEROTONINERGIC AND/OR NOREPINEPHRINERGIC ACTIVITY | ACADIA PHARMACEUTICALS INC. | 2016-12-15 | — | — | US | disclosed |
| US-20160318847-A1 | SUBSTITUTED PHENETHYLAMINES WITH SEROTONINERGIC AND/OR NOREPINEPHRINERGIC ACTIVITY | ACADIA PHARMACEUTICALS INC. | 2016-11-03 | — | — | US | disclosed |
| US-9458082-B2 | Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity | AUSPEX PHARMACEUTICALS, INC. (US) | 2016-10-04 | — | — | US | disclosed |
| WO-2005108338-A1 | NOVEL THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER, METABOLIC DISEASES AND SKIN DISORDERS | AUSPEX PHARMACEUTICALS (US) | 2005-11-17 | — | — | WO | disclosed |
| US-20050234050-A1 | Ph sensitive prodrugs of 2,6-diisopropylphenol | AUSPEX PHARMACEUTICALS INC | 2005-10-20 | — | — | US | disclosed |
| US-6951843-B2 | Peptide derivatives and their pharmaceutically acceptable salts, thereof, processes for preparation of both and use thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2005-10-04 | — | — | US | disclosed |
| WO-2005049582-A1 | METHOD OF PREPARATION OF NOVEL NUCLEOSIDE ANALOGS AND USES | AUSPEX PHARMACEUTICALS, INC. (US) | 2005-06-02 | — | — | WO | disclosed |
| WO-2005011573-A2 | NOVEL THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER, METABOLIC DISEASES AND SKIN DISORDERS | AUSPEX PHARMACEUTICALS, INC. (US) | 2005-02-10 | — | — | WO | disclosed |
| WO-2005000233-A2 | NOVEL THERAPEAUTIC AGENTS FOR THE TREATMENT OF CANCER, METABOLIC DISEASES AND SKIN DISORDERS | AUSPEX PHARMACEUTICALS (US) | 2005-01-06 | — | — | WO | disclosed |
| EP-1333024-A1 | PEPTIDE DERIVATIVES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, PROCESSES FOR PREPARATION OF BOTH, AND USE THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2003-08-06 | — | — | EP | disclosed |
| US-20030087828-A1 | Peptide derivatives and pharmaceutically acceptable salts, thereof, processes for preparation of both, and use thereof | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2003-05-08 | — | — | US | disclosed |