Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9978780 | 0.83 | GBA1 (0.47) | GBA1SLC6A2SLC6A4SLC6A3OPRD1 | |
| SCHEMBL8806240 | 0.81 | SIGMAR1 (0.46) | SLC6A2SLC6A4SIGMAR1MAOATAAR1 | |
| SCHEMBL11451845 | 0.81 | GBA1 (0.53) | GBA1SLC6A2SLC6A4SIGMAR1SLC6A3 | |
| SCHEMBL28282168 | 0.80 | CPN1 (0.42) | SLC6A2SLC6A4SIGMAR1MAOATAAR1 | |
| Hydrochloric Acid SCHEMBL7402372 | 0.79 | SLC6A2 (0.39) | GBA1SLC6A2SLC6A4SLC6A3HRH1 | |
| SCHEMBL15265050 | 0.79 | GBA1 (0.50) | GBA1SLC6A2SLC6A4SIGMAR1SLC6A3 | |
| SCHEMBL27478385 | 0.79 | DPP4 (0.51) | GBA1SLC6A2SLC6A4SIGMAR1MAOA | |
| SCHEMBL7304914 | 0.79 | GBA1 (0.50) | GBA1SLC6A2SLC6A4SIGMAR1SLC6A3 | |
| SCHEMBL16056164 | 0.78 | SLC6A2 (0.47) | GBA1SLC6A2SLC6A4SLC6A3SOS1 | |
| Ammonia Solution, Strong SCHEMBL27382599 | 0.77 | GBA1 (0.49) | GBA1SLC6A2SLC6A4SIGMAR1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020264187-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER, VIRAL INFECTIONS, AND ALLERGIC CONDITIONS | JANETKA JAMES (US) | 2020-12-30 | — | — | WO | disclosed |