Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.41 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30294563 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MAPTCLCN2AKR1C3AKR1C2 | |
| SCHEMBL6035661 | 0.94 | CLCN2 (0.54) | ALDH1A1MAPTCLCN2AKR1C3AKR1C2 | |
| SCHEMBL30294548 | 0.83 | CLCN2 (0.57) | ALDH1A1MAPTCLCN2AKR1C3AKR1C2 | |
| SCHEMBL22852841 | 0.83 | CLCN2 (0.57) | ALDH1A1MAPTCLCN2AKR1C3AKR1C2 | |
| SCHEMBL22852820 | 0.82 | IDO1 (0.44) | ALDH1A1MAPTCLCN2MEN1KMT2A | |
| SCHEMBL30294688 | 0.82 | IDO1 (0.44) | ALDH1A1MAPTCLCN2MEN1KMT2A | |
| SCHEMBL5388933 | 0.82 | MAPT (0.51) | ALDH1A1MAPTCLCN2MEN1KMT2A | |
| SCHEMBL22853383 | 0.82 | P2RY4 (0.56) | CLCN2AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL30294653 | 0.82 | P2RY4 (0.56) | CLCN2AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL22853121 | 0.81 | IDO1 (0.48) | ALDH1A1MAPTCLCN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020261114-A1 | 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-12-30 | — | — | WO | disclosed |