Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.45 |
| ▸ | PDE5A | O76074 | 2/20 | 0.44 |
| ▸ | PDE6D | O43924 | 1/20 | 0.44 |
| ▸ | PDE6A | P16499 | 1/20 | 0.44 |
| ▸ | PDE6G | P18545 | 1/20 | 0.44 |
| ▸ | PDE6B | P35913 | 1/20 | 0.44 |
| ▸ | PDE6C | P51160 | 1/20 | 0.44 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30294858 | 1.00 | CDC25B (0.48) | CDC25BALDH1A1RXFP1MRGPRX4SCN8A | |
| SCHEMBL30294309 | 0.92 | CDC25B (0.47) | CDC25BALDH1A1RXFP1MRGPRX4SCN8A | |
| SCHEMBL22853410 | 0.92 | CDC25B (0.47) | CDC25BALDH1A1RXFP1MRGPRX4SCN8A | |
| SCHEMBL22853044 | 0.89 | MAPT (0.49) | CDC25BALDH1A1PDE5APDE6DPDE6A | |
| SCHEMBL30294496 | 0.89 | MAPT (0.49) | CDC25BALDH1A1PDE5APDE6DPDE6A | |
| SCHEMBL22853414 | 0.87 | MRGPRX4 (0.45) | MRGPRX4SCN8ASCN10ACYP1A2CYP2C9 | |
| SCHEMBL30294513 | 0.87 | MRGPRX4 (0.45) | MRGPRX4SCN8ASCN10ACYP1A2CYP2C9 | |
| SCHEMBL22853079 | 0.85 | MPO (0.57) | ALDH1A1RXFP1SCN8ASCN10ACYP2C19 | |
| SCHEMBL30294712 | 0.85 | MPO (0.57) | ALDH1A1RXFP1SCN8ASCN10ACYP2C19 | |
| SCHEMBL22853053 | 0.83 | MRGPRX4 (0.42) | CDC25BMRGPRX4CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020261114-A1 | 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-12-30 | — | — | WO | disclosed |