Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22853711 | 0.94 | GABRA5 (0.39) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL18808051 | 0.92 | GABRA1 (0.41) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL18808052 | 0.92 | GABRA1 (0.41) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL22853772 | 0.92 | GABRA1 (0.38) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL22853765 | 0.92 | BRD4 (0.33) | BRD4HDAC6HDAC1 | |
| Remimazolam SCHEMBL23735014 | 0.91 | GABRA1 (0.42) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| Remimazolam SCHEMBL29579211 | 0.91 | GABRA1 (0.42) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| Remimazolam SCHEMBL846435 | 0.91 | GABRA1 (0.42) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| Remimazolam SCHEMBL29379415 | 0.91 | GABRA1 (0.42) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL22853702 | 0.90 | GABRA1 (0.39) | GABRA1GABRA5GABRA3GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3992194-A1 | BENZODIAZEPINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | West China Hospital, Sichuan University (CN) | 2022-05-04 | — | — | EP | disclosed |
| WO-2020259602-A1 | BENZODIAZEPINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | 四川大学华西医院 | 2020-12-30 | — | — | WO | disclosed |