Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 14/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13335925 | 0.88 | POLB (0.40) | PPARDNPC1ALDH1A1RAB9APOLB | |
| SCHEMBL18503874 | 0.81 | PPARD (0.44) | PPARDALDH1A1POLBTSHRHTT | |
| SCHEMBL11204876 | 0.77 | LOXL2 (0.39) | ALDH1A1LOXL2LMNA | |
| SCHEMBL2616418 | 0.77 | CCR9 (0.43) | ALDH1A1POLBLOXL2HTT | |
| SCHEMBL2646780 | 0.76 | PPARD (0.42) | PPARDNPC1ALDH1A1RAB9APOLB | |
| SCHEMBL4971748 | 0.76 | CA12 (0.56) | PPARDNPC1ALDH1A1RAB9ALOXL2 | |
| SCHEMBL16013946 | 0.76 | GBA1 (0.41) | PPARDNPC1ALDH1A1RAB9ALOXL2 | |
| SCHEMBL18379317 | 0.75 | CA1 (0.55) | ALDH1A1POLBLOXL2 | |
| SCHEMBL21553529 | 0.74 | PPARD (0.36) | PPARDNPC1ALDH1A1RAB9ATSHR | |
| SCHEMBL24499303 | 0.74 | ALDH1A1 (0.37) | ALDH1A1POLBLOXL2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020261294-A1 | NOVEL APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS | MANKIND PHARMA LTD. (IN) | 2020-12-30 | — | — | WO | disclosed |