Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116629 | 0.85 | KMT2A (0.61) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL24185211 | 0.83 | MGLL (0.48) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL13006682 | 0.81 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL24185272 | 0.80 | HPGD (0.54) | ALDH1A1KMT2ALMNAPOLBMGLL | |
| SCHEMBL17319229 | 0.78 | GAA (0.64) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL20085460 | 0.77 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL19473338 | 0.77 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL19226514 | 0.77 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL18068293 | 0.77 | NPC1 (0.65) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL20085608 | 0.77 | KMT2A (0.58) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020261294-A1 | NOVEL APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS | MANKIND PHARMA LTD. (IN) | 2020-12-30 | — | — | WO | disclosed |