Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29561474 | 0.87 | KMT2A (0.58) | TLR2KMT2AMDM4TP53 | |
| SCHEMBL17615128 | 0.87 | KMT2A (0.58) | TLR2KMT2AMDM4TP53 | |
| SCHEMBL14090285 | 0.86 | TLR2 (0.53) | TLR2KMT2AMDM4TP53CASP3 | |
| SCHEMBL16095188 | 0.84 | MDM4 (0.58) | TLR2KMT2AMDM4TP53CASP3 | |
| SCHEMBL16095190 | 0.84 | MDM4 (0.58) | TLR2KMT2AMDM4TP53CASP3 | |
| SCHEMBL29541007 | 0.84 | MDM4 (0.58) | TLR2KMT2AMDM4TP53CASP3 | |
| SCHEMBL29398313 | 0.84 | MDM4 (0.58) | TLR2KMT2AMDM4TP53CASP3 | |
| SCHEMBL29398093 | 0.84 | MDM4 (0.58) | TLR2KMT2AMDM4TP53CASP3 | |
| Hydrochloric Acid SCHEMBL25358854 | 0.83 | MDM4 (0.57) | TLR2KMT2AMDM4TP53CASP3 | |
| SCHEMBL17282987 | 0.83 | KMT2A (0.55) | TLR2KMT2AMDM4TP53CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020264572-A1 | FRAGMENT-BASED SCREENING TO IDENTIFY SMALL MOLECULES THAT SELECTIVELY BIND RNA | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-12-30 | — | — | WO | disclosed |