Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15267217 | 0.83 | ALDH1A1 (0.62) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL20191358 | 0.79 | ALDH1A1 (0.56) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL20097895 | 0.77 | ALDH1A1 (0.55) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL26829373 | 0.76 | ALDH1A1 (0.53) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL9938923 | 0.75 | TSHR (0.45) | ALDH1A1KMT2AL3MBTL1TSHRLMNA | |
| SCHEMBL6398410 | 0.74 | ALDH1A1 (0.63) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL13234401 | 0.73 | ALDH1A1 (0.70) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL13234399 | 0.73 | ALDH1A1 (0.70) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL13234406 | 0.73 | ALDH1A1 (0.70) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL13234395 | 0.73 | ALDH1A1 (0.70) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200406252-A1 | COATINGS WITH IMMOBILIZED AFFINITY LIGANDS AND ENZYMES AND USE THEREOF IN LIQUID CHROMATOGRAPHY ASSAYS | WATERS TECHNOLOGIES CORPORATION (US) | 2020-12-31 | — | — | US | disclosed |