Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944010 | 0.80 | TSHR (0.46) | TSHRKCNN4KMT2AMAPTKDM4E | |
| SCHEMBL9937737 | 0.77 | ESR1 (0.44) | TSHRMAPTESR1ESR2HPGD | |
| SCHEMBL22854889 | 0.75 | ALDH1A1 (0.56) | TSHRKMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL10862341 | 0.75 | MAPT (0.47) | TSHRMAPTESR1ESR2HPGD | |
| SCHEMBL10864231 | 0.71 | CES1 (0.48) | TSHRKMT2AMAPTESR1ESR2 | |
| SCHEMBL22279924 | 0.71 | KMT2A (0.42) | TSHRKCNN4KMT2AMAPTESR1 | |
| SCHEMBL14760178 | 0.70 | MAPT (0.47) | TSHRKCNN4KMT2AMAPTESR1 | |
| SCHEMBL9223978 | 0.68 | SMN1; SMN2 (0.41) | TSHRKCNN4KMT2AMAPTESR1 | |
| SCHEMBL15053482 | 0.68 | ALDH1A1 (0.44) | TSHRKMT2AMAPTKDM4EHPGD | |
| SCHEMBL7944012 | 0.68 | TSHR (0.54) | TSHRKMT2AMAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079583-A1 | SYSTEM PROVIDING CONTROLLED DELIVERY OF GASEOUS CO FOR CARBONYLATION REACTIONS | AARHUS UNIVERSITET (DK) | 2012-06-21 | — | — | WO | disclosed |