Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NT5E | P21589 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | CHKA | P35790 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2520516 | 1.00 | AHCY (0.47) | AHCYLMNANT5EHIF1ACHKA | |
| SCHEMBL2520562 | 0.90 | AHCY (0.47) | AHCYLMNANT5EHIF1ACHKA | |
| SCHEMBL25659855 | 0.90 | AHCY (0.45) | AHCYLMNANT5EHIF1ACHKA | |
| SCHEMBL25867818 | 0.88 | PNP (0.39) | LMNAADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL2524440 | 0.88 | PDE4D (0.53) | LMNANT5EADORA3ADORA2AADORA1 | |
| SCHEMBL21709764 | 0.88 | AHCY (0.34) | AHCYLMNANT5EHIF1ACHKA | |
| SCHEMBL12214180 | 0.85 | AHCY (0.41) | AHCYLMNANT5EHIF1ACHKA | |
| SCHEMBL13581562 | 0.85 | AHCY (0.42) | AHCYLMNANT5EHIF1ACHKA | |
| SCHEMBL29790376 | 0.84 | AHCY (0.41) | AHCYLMNANT5EHIF1ACHKA | |
| SCHEMBL21709653 | 0.83 | AHCY (0.40) | AHCYLMNANT5EHIF1ACHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050961-A1 | ANTIVIRAL PRODRUGS AND FORMULATIONS THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-03-18 | — | — | WO | disclosed |
| WO-2021021717-A1 | ADENOSINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | BRII BIOSCIENCES, INC. (US) | 2021-02-04 | — | — | WO | disclosed |
| WO-2020263660-A1 | PROCESS FOR THE PREPARATION OF 2-FLUOROADENINE | MERCK SHARP & DOHME CORP. (US) | 2020-12-30 | — | — | WO | disclosed |