Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.31 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31117131 | 0.90 | — | — | |
| SCHEMBL8209830 | 0.78 | CES2 (0.48) | CES2CES1HDAC8HDAC6GAA | |
| SCHEMBL19487315 | 0.78 | CES2 (0.42) | CES2CES1HDAC8HDAC6GAA | |
| SCHEMBL29333139 | 0.76 | CES2 (0.46) | CES2CES1HDAC8HDAC6GAA | |
| SCHEMBL16976843 | 0.76 | CES2 (0.46) | CES2CES1HDAC8HDAC6GAA | |
| SCHEMBL9609535 | 0.76 | CES2 (0.46) | CES2CES1HDAC8HDAC6GAA | |
| SCHEMBL6122262 | 0.71 | CES2 (0.35) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL13468227 | 0.71 | CES2 (0.40) | CES2CES1HDAC8HDAC6GAA | |
| SCHEMBL6122268 | 0.71 | CES2 (0.35) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL20356221 | 0.71 | ATM (0.33) | CES2CES1ALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11342516-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2022-05-24 | — | — | US | disclosed |
| US-20200411774-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2020-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11342516-B2 | Organic electroluminescent materials and devices | ORC3, OCIAD1, ICOSLG | CES2 2122/4885CES1 3803/4885HDAC8 2599/4885 |
| US-20200411774-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | ORC3, OCIAD1, ICOSLG | CES2 2122/4885CES1 3803/4885HDAC8 2599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.