Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29333139 | 0.83 | CES2 (0.46) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL16976843 | 0.83 | CES2 (0.46) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL19487315 | 0.80 | CES2 (0.42) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL22855852 | 0.78 | CES2 (0.40) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL31365247 | 0.77 | CES2 (0.43) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL164962 | 0.76 | CES2 (0.44) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL20954491 | 0.76 | CES2 (0.44) | CES2CES1HDAC8HDAC6TSHR | |
| Cicrotoic Acid SCHEMBL2773332 | 0.76 | CES2 (0.44) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL166051 | 0.76 | CES2 (0.44) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL1794601 | 0.76 | CES2 (0.44) | CES2CES1HDAC8HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968144-A1 | LIQUID CURABLE RESIN COMPOSITION FOR FAT FIBRE | DSM N.V. (NL) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998041483-A1 | LIQUID CURABLE RESIN COMPOSITION FOR FAT FIBRE | DSM N.V. (NL) | 1998-09-24 | — | — | WO | disclosed |