SCHEMBL22855965

SCHEMBL22855965

COC(C)COC(C)(C)CCOC(=O)C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.37
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21419988 0.86 CYP4F2 (0.30)
SCHEMBL22855964 0.86 PRKCA (0.33) PRKCAPOLBGAANPSR1
SCHEMBL17828577 0.79 PRKCA (0.50) PRKCAPOLBGAANPSR1
SCHEMBL26040609 0.78
SCHEMBL19865688 0.76 POLB (0.36) PRKCAPOLBGAANPSR1
SCHEMBL17874894 0.75 MAPK1 (0.35)
SCHEMBL13073713 0.75 POLB (0.40) PRKCAPOLBGAANPSR1
SCHEMBL24901922 0.75 CYP1A2 (0.35)
SCHEMBL20289859 0.72 PRKCA (0.34) PRKCAPOLBGAANPSR1
SCHEMBL22697443 0.71 POLB (0.35) PRKCAPOLBGAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200405881-A1 CELL BASED METHODS AND COMPOSITIONS FOR THERAPEUTIC AGENT DELIVERY AND TREATMENTS USING SAME UNIVERSITY OF WASHINGTON (US) 2020-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200405881-A1 CELL BASED METHODS AND COMPOSITIONS FOR THERAPEUTIC AGENT DELIVERY AND TREATMENTS USING SAME CXCL12, CD47, CD44 PRKCA 1315/4885POLB 2877/4885GAA 1457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.