SCHEMBL22697443

SCHEMBL22697443

CC(C)(CCOC(=O)C(C)(C)C)OCC(C)(C)C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PRKCA P17252 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23996054 0.78 POLB (0.33) POLBGAANPSR1PRKCA
SCHEMBL19865688 0.76 POLB (0.36) POLBGAANPSR1PRKCA
SCHEMBL8962465 0.76 PRKCA (0.41) POLBGAANPSR1PRKCA
SCHEMBL13073713 0.75 POLB (0.40) POLBGAANPSR1PRKCA
SCHEMBL1753756 0.72 POLB (0.43) POLBGAANPSR1PRKCA
SCHEMBL9925701 0.72 GAA (0.43) POLBGAANPSR1PRKCA
SCHEMBL22856131 0.71 PRKCA (0.33) POLBGAANPSR1PRKCA
SCHEMBL22855965 0.71 PRKCA (0.37) POLBGAANPSR1PRKCA
SCHEMBL4258156 0.71 POLB (0.48) POLBGAANPSR1PRKCA
SCHEMBL22855964 0.70 PRKCA (0.33) POLBGAANPSR1PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200369703-A1 Modified oligonucleotides and compound that can be used for synthesizing same GUANGZHOU RIBOBIO CO LTD (CN) 2020-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200369703-A1 Modified oligonucleotides and compound that can be used for synthesizing same POLRMT, RNASE1, ADAR POLB 82/4885GAA 380/4885NPSR1 2569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.